Pau Sancho-Bru

Grup de recerca

Plasticitat i reparació tissular en malalties hepàtiques Group leader (R4)

psancho@recerca.clinic.cat 0000-0001-5569-9259

Segueix-lo/a a:

El perfil de ResearchGate de Pau . Aquest enllaç s'obre en una nova pestanya.

Publicacions destacades

Ductular reaction-associated neutrophils promote biliary epithelium proliferation in chronic liver disease

Autors:
Arino, S; Aguilar-Bravo, B; Coll, M; Lee, WY; Peiseler, M;

(...)

Planas, AM; Gines, P; Moles, A; Kubes, P; Sancho-Bru, P.

Referència: Journal Of Hepatology 2023.
Hepatocyte dedifferentiation profiling in alcohol-related liver disease identifies CXCR4 as a driver of cell reprogramming

Autors:
Aguilar-Bravo, B; Ariño, S; Blaya, D; Pose, E; de la Torre, RAMG;

(...)

Bataller, R; Lozano, JJ; Ginès, P; Mathurin, P; Sancho-Bru, P.

Referència: Journal Of Hepatology 2023.
Ductular Reaction Promotes Intrahepatic Angiogenesis Via Slit2-Robo1 Signaling

Autors:
Coll, M; Ariño, S; Martínez-Sánchez, C; Garcia-Pras, E; Gallego, J;

(...)

Bataller, R; Geng, JG; Ginès, P; Fernandez, M; Sancho-Bru, P.

Referència: Hepatology 2022.
Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells

Autors:
Vallverdu, Julia; Martinez Garcia de la Torre, Raquel A; Mannaerts, Inge; Verhulst, Stefaan; Smout, Ayla;

(...)

Martinez-Sanchez, Celia; Blaya, Delia; Verfaillie, Catherine M; van Grunsven, Leo A; Sancho-Bru, Pau.

Referència: Nature Protocols 2021.
Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure

Autors:
Blaya, D; Pose, E; Coll, M; Lozano, JJ; Graupera, I;

(...)

Solà, E; Caballería, J; Trebicka, J; Ginès, P; Sancho-Bru, P.

Referència: Jhep Rep 2021.
Ductular reaction cells display an inflammatory profile and recruit neutrophils in alcoholic hepatitis

Autors:
Aguilar-Bravo B; Rodrigo-Torres D; Ariño S; Coll M; Pose E;

(...)

Bataller R; Caballería J; José Lozano J; Ginès P; Sancho-Bru P .

Referència: Hepatology 2019.
Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

Autors:
Coll M; Perea L; Boon R; Leite S; Vallverdú J;

(...)

Sokal E; Lozano J; van Grunsven L; Verfaillie C; Sancho-Bru P.

Referència: Cell Stem Cell 2018.

Projectes destacats

Patient-derived liver biopsy-organoids for personalized medicine in NAFLD (Non-Alcoholic Fatty Liver Disease): towards real time assessment of drug response (B-ORG)

Investigador/a principal: Pau Sancho Bru

Finançador: Ministerio de Ciencia e Innovación

Codi: IBEC_ProyectCompl22

Durada: 13/04/2023 - 31/12/2024
Dissecting the role of the 14q32 region in hepatoblastoma Hblast14

Investigador/a principal: Pau Sancho Bru

Finançador: Worldwide Cancer Research

Codi: INT_WWCR_22

Durada: 01/04/2023 - 31/03/2026
Off the shelf hepatic stellate cells for liver disease modeling and drug screening

Investigador/a principal: Pau Sancho Bru

Finançador: Instituto de Salud Carlos III

Codi: FIS_DTS22

Durada: 01/01/2023 - 31/12/2025
Discovering chronic inflammation biomarkers that define key stages in the Healthy-to-NASH transition to inform early prevention and treatment strategies. (Halt-RONIN)

Investigador/a principal: Pau Sancho Bru

Finançador: European Commission

Durada: 01/12/2022 - 30/11/2026
Mechanisms of impaired liver regeneration in alcoholic liver disease: drivers and therapeutic targets

Investigador/a principal: Pau Sancho Bru

Finançador: Instituto de Salud Carlos III

Codi: PI20/00765

Durada: 01/01/2021 - 31/12/2023

Pau Sancho-Bru

Grup de recerca

Publicacions destacades

Ductular reaction-associated neutrophils promote biliary epithelium proliferation in chronic liver disease

Hepatocyte dedifferentiation profiling in alcohol-related liver disease identifies CXCR4 as a driver of cell reprogramming

Ductular Reaction Promotes Intrahepatic Angiogenesis Via Slit2-Robo1 Signaling

Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells

Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure

Ductular reaction cells display an inflammatory profile and recruit neutrophils in alcoholic hepatitis

Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

Projectes destacats

Patient-derived liver biopsy-organoids for personalized medicine in NAFLD (Non-Alcoholic Fatty Liver Disease): towards real time assessment of drug response (B-ORG)

Dissecting the role of the 14q32 region in hepatoblastoma Hblast14

Off the shelf hepatic stellate cells for liver disease modeling and drug screening

Discovering chronic inflammation biomarkers that define key stages in the Healthy-to-NASH transition to inform early prevention and treatment strategies. (Halt-RONIN)

Mechanisms of impaired liver regeneration in alcoholic liver disease: drivers and therapeutic targets

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