Antonio Postigo

ICREA-IDIBAPS

Grup de recerca

Regulació gènica en cèl·lules mare, la plasticitat i diferenciació cel·lular, i el càncer Group leader (R4)

idib412@recerca.clinic.cat 0000-0003-4605-2634

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El compte de twitter de Antonio . Aquest enllaç s'obre en una nova pestanya.

Publicacions destacades

Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation

Autors:
Martinez-Campanario, M C; Cortes, Marlies; Moreno-Lanceta, Alazne; Han, Lu; Ninfali, Chiara;

(...)

Escola-Gil, Joan C; de Frutos, Pablo Garcia; Andres, Vicente; Melgar-Lesmes, Pedro; Postigo, Antonio.

Referència: Nature Communications 2023.
Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation

Autors:
Cortes, Marlies; Brischetto, Agnese; Martinez-Campanario, M C; Ninfali, Chiara; Dominguez, Veronica;

(...)

Pintado, Belen; Morales-Ruiz, Manuel; Castro, Pedro; Canete, Juan D; Postigo, Antonio.

Referència: Nature Communications 2023.
The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2

Autors:
Ninfali, C; Cortés, M; Martínez-Campanario, MC; Domínguez, V; Han, L;

(...)

Esteve-Codina, A; Enrich, C; Pintado, B; Garrabou, G; Postigo, A.

Referència: Proceedings Of The National Academy Of Sciences Of The United States Of America 2023.
The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2

Autors:
Ninfali, C; Siles, L; Esteve-Codina, A; Postigo, A;

Referència: Cell Reports 2023.
ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells

Autors:
de Barrios, Oriol; Sanchez-Moral, Lidia; Cortes, Marlies; Ninfali, Chiara; Profitos-Peleja, Nuria;

(...)

Castells, Antoni; Maurel, Joan; Salas, Azucena; Dean, Douglas C; Postigo, Antonio.

Referència: Gut 2019.
ZEB1 protects skeletal muscle from damage and is required for its regeneration

Autors:
Siles, L; Ninfali, C; Cortes, M; Darling, DS; Postigo, A;

Referència: Nature Communications 2019.
Regulation of muscle atrophy-related genes by the opposing transcriptional activities of ZEB1/CtBP and FOXO3

Autors:
Ninfali C; Siles L; Darling D; Postigo A;

Referència: Nucleic Acids Research 2018.
Mitotic polarization of transcription factors during asymmetric division establishes fate of forming cancer cells

Autors:
Liu, Yongqing; Siles, Laura; Lu, Xiaoqin; Dean, Kevin C; Cuatrecasas, Miriam;

Postigo, Antonio; Dean, Douglas C.

Referència: Nature Communications 2018.
Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles

Autors:
Cortes, Marlies; Sanchez-Moral, Lidia; de Barrios, Oriol; Fernandez-Acenero, Maria J.; Martinez-Campanario, M. C.;

(...)

Darling, Douglas S.; Gyorffy, Balazs; Lawrence, Toby; Dean, Douglas C.; Postigo, Antonio..

Referència: Embo Journal 2017.
ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1

Autors:
de Barrios, Oriol; Gyorffy, Balazs; Jesus Fernandez-Acenero, Maria; Sanchez-Tillo, Ester; Sanchez-Moral, Lidia;

(...)

Roue, Gael; Casal, Jose I; Darling, Douglas S; Castells, Antoni; Postigo, Antonio.

Referència: Gut 2017.

Projectes destacats

Cooperation and competition between colorectal carcinomas (CRC) and their tumor microenvironment: Validation of ZEB factors as prognostic and predictive biomarkers and therapeutic targets in CRC.

Investigador/a principal: Antonio Postigo

Finançador: Fundació Olga Torres

Codi: FUND.OLGATORRES_19_3

Durada: 01/01/2020 - 31/12/2021
Validation of ZEB factors as prognostic and predictive biomarkers and therapeutic targets in CRC

Investigador/a principal: Antonio Postigo

Finançador: Asociación Española Contra el Cáncer (AECC).

Codi: AECC_2019

Durada: 01/11/2019 - 31/10/2022
Validation of ZEB2 as a predictive predictive biomarker and potential therapeutic target in Duchenne muscular dystrophy

Investigador/a principal: Antonio Postigo

Finançador: Duchenne Parent Project

Codi: DPP-E-2018

Durada: 16/12/2018 - 15/12/2020

Antonio Postigo

Grup de recerca

Publicacions destacades

Projectes destacats

Cooperation and competition between colorectal carcinomas (CRC) and their tumor microenvironment: Validation of ZEB factors as prognostic and predictive biomarkers and therapeutic targets in CRC.

Validation of ZEB factors as prognostic and predictive biomarkers and therapeutic targets in CRC

Validation of ZEB2 as a predictive predictive biomarker and potential therapeutic target in Duchenne muscular dystrophy

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